Our research focuses on bioinformatics analysis of biological data and the application of biological computing to solve complex problems related to agriculture, veterinary and medical science.
Gastropod mucus and its utilization:
Several gastropod species (snails and slugs) damage farm and ornamental plants. We analyze their mucus contents with omics technology and bioinformatics tools to gain an in-depth comprehension of the properties and constituents. Several novel bioactive properties have been found and we hope that these will add more economic values to these invasive snails as well as their control. Support from the private company sponsor (Do Day Dream Co. Ltd. Pub.) allows expansion of the gastropod research into a wide array of interests relevant to health and medicine. Basic genetics, transcriptomics, and proteomics of the gastropods are our current focus to understand their life and behaviors. We also collaborated with the Faculty of Fisheries to work on some marine bivalves.
Human and animal pathogens:
Collaborations with government and private organizations give us opportunities to work with human and animal pathogens including
- protozoan parasites, Leishmania sp. with Phramongkutklao College of Medicine;
- Pasteurella multocida and other respiratory bacterial pathogens in pigs, cattle, and buffaloes with the National Institute of Animal Health, Department of Livestock Development, Ministry of Agriculture and Cooperatives, Universiti of Putra Malaysia, Malaysia, and BF Feed Com. Ltd.;
- bacterial and viral pathogens in cats and dogs with Department of Veterinary, KU;
- pathogens in aquatic animals with the Department of Biochemistry, KU, and Department of Public Health, Mahidol University;
- Acne-causing bacteria from the skin and accommodation with the private company.
Basically, we computationally analyze the pathogen genetics and genomes to understand their phenotypic difference, virulence, pathogenicity, outbreak, bacteria-bacteria interaction, and to identify potential targets that could be useful for vaccine and drug development.
Human whole genome and exome data analysis:
This is another challenging topic for bioinformaticians to computationally analyze and understand our selves as a human being. We employ software and develop an analytic workflow to simplify the human genomic and exomic data which will benefit medical geneticists or related occupations aiding the interpretation and understanding of human diseases and abnormalities.
Our lab member activities:
Yearly, we open the application from students for internship and research projects. If you are interested, please feel free to contact and discuss your interest with us. Research grants and scholarships are also available.